Conveners
PAR 1
- Heinz Gaeggeler (Paul Scherrer Institut)
- Jiří Mizera (Nuclear Physics Institute, Academy of Sciences of the Czech Republic)
Theranostic medicine is a new integrated therapeutic system which can diagnose, deliver targeted therapy and monitor the response to therapy. Many of the “neutron rich” radionuclides that emit both imaging photons as well as therapeutic beta particles and which would be potentially excellent choices for metabolic radiotherapy and theranostic applications are produced by nuclear reactor with a...
Reactor production of radionuclides is well established. However, more and more new, unconventional production routes are being requested as consequence of new applications in nuclear medicine. In order to be able to fulfil new irradiation requests it is important to design flexible irradiation facilities. Here, we present new irradiation facility with built in flexibility allowing tuning the...
In this study, we produced Tc isotopes with high energy gamma emitting for developing of Compton camera imaging instead of SPECT measurement with 99mTc. Technetium-99m is used in radioactive diagnostic tests, for example as a radioactive tracer that a nuclear medical gamma camera can detect in human body. It is well suited to the role because it emits readily detectable 141 keV gamma rays, and...
Diagnostic imaging using $^{99m}$Tc ($T_{1/2}$ = 6.0 h), which is produced from the decay of $^{99}$Mo ($T_{1/2}$ = 66 h), is relying on the production of $^{99}$Mo from nuclear reactors to be shutdown. Alternative routes to produce the $^{99}$Mo and $^{99m}$Tc isotopes are being investigated. One of the reactions to create $^{99}$Mo is the $^{96}$Zr($\alpha$,n)$^{99}$Mo reaction. There are...
99mTc is very important for medical practice, and efforts to develop the best procedure for the production of its parent 99Mo for the subsequent use in 99mTc generators are being made for more than four decades. For this purpose, a composite ceramic target containing HEU dioxide and a filler metallic powder (Al, Mg, etc.) has been irradiated in a high-flux reactor to obtain concentrate...
Theranostics, which combines therapy and diagnosis, is one of hot topics in nuclear medicine. Theranostic RI to provide such new medical treatment have been investigated. We focus on $^{177}$Lu (T$_{1/2}$ = 6.6 d), which is one of candidates of theranostic RI since it emits both beta particles and gamma-rays, which are suitable for therapy and diagnosis, respectively. However, the production...
