Speaker
Description
Triskem develops extraction chromatographic resins specific for radionuclides and/or group of radionuclides that are used in different fields such as environmental monitoring, decommissioning, nuclear medicine, and more. Depending on the application, the resin format is not always the most efficient option. This is why in the last years Triskem has initiated the development of new formats such as selective discs/filtering membranes and impregnated Thin Layer Chromatography supports. TK100 Discs are used in DGT devices for the accurate quantification of trace-level (μg L–1) Sr and Pb concentrations and isotope ratios [δSRM 987(87Sr/86Sr) and δSRM 981(207Pb/206Pb)] in labile, bioavailable element fractions in soils (1,2). TK201 Discs have been used for the preconcentration of Tc-99 from hospital waster waters before purification and quantification by ICP-MS (3). In the same format, TK-GA Discs have been developed to trap actinides from water samples during filtration and thus allowing subsequent alpha spectrometry analysis (4).
TLC supports functionalized via impregnation with selective extractants is another field of development to provide mostly nuclear medicine with fast quality control regarding labelling yields and radionuclidic impurity determination. DGA Sheets have been developed by Kozempel et al. at CTUP for the determination of radionuclidic impurities e.g. in Ra-223, Ac-225 or Pb-212 solution for use in labelling. They further have been used to quantify Ra-Macropa labelling yields. CU Sheets have been developed to facilitate the analysis of Cu radiolabelled peptides.
Further, the development of other selective Discs/filtering membranes and ITLC supports currently being developed are presented here.
Key words: impregnated discs, iTLC, TK100 discs, TK-GA discs, DGA Sheets, CU Sheets.
References
(1) S. Wagner, J. Santner, J. Irrgeher et al. Selective Diffusive Gradients in Thin Films (DGT) for the Simultaneous Assessment of Labile Sr and Pb Concentrations and Isotope Ratios in Soils. Anal Chem, 2022, 94, 16, 6338-6346
https://doi.org/10.1021/acs.analchem.2c00546
(2) S. Wagner, J. Santner, M; Puschenreiter, et al. Prediction of Radiogenic Sr and Pb Isotope Signatures in Plants using Diffusive Gradients in Thin Films. Analytical and Bioanalytical Chemistry, 2026, 418, 1541–1555
https://doi.org/10.1007/s00216-026-06315-6
(3) M. Horstmann , C. Derrick Quarles Jr , S. Happel et al. : Quantification of technetium-99 in wastewater by means of automated on-line extraction chromatography – anion-exchange chromatography – inductively coupled plasma-mass spectrometry. J. Anal. At. Spectrom., 2024, 39, 2774-2782, https://doi.org/10.1039/D4JA00270A
(4) C. Bailly et al. Selective impregnated Membrane Filters for Direct Alpha Spectrometric Analysis of Actinides; Applied Radiation and Isotopes, in preparation