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RadChem 2010

18–23 Apr 2010
Casino Conference Centre
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Session

Nuclear Methods in Medicine, Radiopharmaceuticals and Diagnostics, Labelled Compounds 2

RF2
22 Apr 2010, 10:00
Casino Conference Centre

Casino Conference Centre

Reitenbergerova 4/95, Marianske Lazne, Czech Republic

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  1. 216. In vivo generators – recoil and conversion electrons considerations
    Dr Jan Rijn Zeevaart (Radiochemistry, Necsa)
    22/04/2010, 10:00
    Nuclear Methods in Medicine, Radiopharmaceuticals and Radiodiagnostics, Labelled Compounds
    Verbal
    The use of radionuclides as potential therapeutic radiopharmaceuticals is increasingly investigated. An important aspect is the delivery of the radionuclide to the target, i.e. the radionuclide is not lost from the chelating agent. For in vivo generators it is not only the log K of complexation between the metal ion and the chelator that is important but whether the daughter radionuclide stays...
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  2. 326. Radiometric determination of enzyme activities, exemplified by several key enzymes of thyroid hormone metabolism
    Dr Stanislav Pavelka (Dept. of Radiometry, Inst. of Physiolgy, ASCR Prague; and Inst. of Biochemistry, Masaryk Univ. Brno, Czech Rep.)
    22/04/2010, 10:30
    Nuclear Methods in Medicine, Radiopharmaceuticals and Radiodiagnostics, Labelled Compounds
    Verbal
    Radiometric enzyme assays are based on the conversion of radio-labeled substrates to labeled products, and on the measurement of radioactivity of either products or residual substrate after their quantitative separation. In the present studies, we aimed to establish valid assay conditions for radiometric determination of the activities of several enzymes, which are involved in the metabolism...
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  3. 182. MIBG - structure revisited
    Prof. Ladislav Lešetický (Faculty of Science, Charles University)
    22/04/2010, 10:45
    Nuclear Methods in Medicine, Radiopharmaceuticals and Radiodiagnostics, Labelled Compounds
    Verbal
    The synthesis, labeling and careful spectroscopic investigation of meta-iodo-benzyl guanidin has been performed. As result of ESI MS and single crystal X-ray diffraction the corect structure is meta-iodo-benzyl guanidine hemisulfate hemihydrate (2 MIBG. H2SO4.H2O).
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