Speaker
Description
Radiotherapy with nanoparticles has been widely investigated, showing an energy dependence performance. A compact radiotherapy equipment providing energy tuneable X-rays is highly demanded. Inverse Compton Scattering (ICS) source can offer quasi-monochromatic and continuously energy tuneable X-rays, enabling optimization of radiation enhancement effect for various nanomaterials. This study simulated nanoparticle dose enhancement with an ICS source using the Geant4. The radiation enhancement effect of a typical nanomaterial, i.e., gold nanoparticles (GNPs), was evaluated and compared with the conventional X-ray tube. The result showed the implementation of an ICS source, with a higher DEF at optimal energy, is feasible for enhanced radiotherapy. The continuously energy tuneable property makes it a promising equipment for the application of enhanced radiotherapy with different nanomaterials.